Recently published two-sample Mendelian randomization (MR) studies showed that genetically predicted coffee consumption may be associated with increased risk of Alzheimer’s disease and intracerebral hemorrhage but associated with a decreased risk ...
I know posting this sucks but the more you know. Better to know than not know.
I’m sure I’ve missed it, but what exactly have they considered as “high coffee consumption”? Some of their findings show some level of coffee consumption can be beneficial, or inconclusive. Which is usually why most of these studies can be summed up with… just don’t overdo it.
High coffee consumption was defined as ≥4 cups per day in most original studies. Seventeen studies used a definition of ≥6 cups per day. Low/no coffee consumption was defined as <1 cup per day in most original studies. Fifteen studies used a definition of <2 cups per day. Four studies used a definition of never drinking.
I’m sure I’ve missed it, but what exactly have they considered as “high coffee consumption”? Some of their findings show some level of coffee consumption can be beneficial, or inconclusive. Which is usually why most of these studies can be summed up with… just don’t overdo it.
High coffee consumption was defined as ≥4 cups per day in most original studies. Seventeen studies used a definition of ≥6 cups per day. Low/no coffee consumption was defined as <1 cup per day in most original studies. Fifteen studies used a definition of <2 cups per day. Four studies used a definition of never drinking.
<1 not to be confused with 0.