Yes, that is the scream that sunk his campaign.

Ironically, nobody in the room with Dean noticed anything out of the ordinary—they witnessed what seemed like nothing more than an impassioned speech, with Dean’s famous scream drowned out by the cheers that filled the room. Dean’s audio setup, however, isolated his voice for the television audience, making the “Dean Scream” stand out jarringly and comically. The clip became a sensation on cable news, discussed and replayed countless times over the week between the Iowa Caucus and the New Hampshire primary, a perfect gift for Dean’s detractors.
https://www.history.com/this-day-in-history/the-dean-scream