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The original was posted on /r/science by /u/sometimeshiny on 2026-02-15 03:13:34+00:00.

Original Title: Alzheimer’s disease linked to glutamatergic hyperexcitability in RNAseq analysis of ~2,000 human brains. Amyloid beta increases neuronal calcium influx, promoting heightened excitatory network activation across species. Reducing key network genes suppresses neurodegeneration in Drosophila.