No, that requirement has already been met. The final requirement (which has just been met now) is to reach a total of 1 million signatures. Basically, all requirements are now satisfied

Circadian biology here.

Internal Time, by Till Roenneberg. Written by one of the “old guards” of the circadian field, old enough that he could be considered a founding father of the field in his own right.

The book is written as a collection of short stories, each one about a real circadian experiment or phenomenon that occurred, and the book invites you to interpret and think about the short stories before explaining the deeper biology and history behind the stories. It’s a very fascinating book and quite approachable for a non-scientific audience, though I think it’s very appropriate even for a scientific audience

Explanation: CRISPR-Cas9 is most commonly known to be a gene editor, but since its initial discovery, people have found that with some minor tweaks, CRISPR can be made to do a bunch of other things, things that biologists could have only dreamed of previously.

If you introduce a mutation that deactivates the Cas9 protein, the entire CRISPR complex still binds to DNA. Then, you can essentially glue whatever you want onto this modified Cas9 to produce a bunch of different effects:

• deactivated Cas9, no additional modifications: blocks other proteins from touching the DNA, which suppresses a gene without destroying it
• glue on some transcriptional activators: makes the cell express a gene
• glue on some fluorescent proteins: makes your DNA glow, lets you see where it is

My understanding is that they misunderstood the petition, so this new one is rephrased in an attempt to avoid another misinterpretation

I quite like Strange Horticulture, but it felt too linear for my tastes. This seems like an interesting shakeup of that formula. I’ll keep an eye on it

We might need a bit more context for why you want to do this. Because as far as I can think, I can’t really come up with a reasonable circumstance in which you might want to use an eGPU on a PC

I vouch for Kubuntu. It uses KDE Plasma, which is the exact same UI as SreamOS desktop mode. It’s based on Ubuntu, which is a very popular distro, so there’s a lot of support and apps that are packaged for it

Manjaro vs. SteamOS, likely no benefit. My speculation is that the company probably wanted to develop their own software but didn’t have the technical expertise to develop for Linux. Hence, they partnered with Manjaro. As for why they went with Linux in the first place, it’s likely because Windows is a mess and they likely considered that Linux would be a more marketable (and cheaper) operating system.

And yes, these products aren’t particularly expanding the market, but it seems that companies would still like to throw their hat into the ring, if only because getting in early means that they’ll have a more dedicated fanbase for their later handheld products

Primer, if you like hard sci-fi. It’s an indie movie about time travel, and it’s got perhaps the most fleshed out time travel mechanic out of all movies I’ve seen. Last I checked, the director posted the full movie on YouTube for free

Many people have a misunderstanding of what the Stop Killing Games movement is about. It’s about trying to get governments to pass a law that requires game developers to have a plan in place for when they shut down the servers of online games. In the current gaming landscape, games can be taken offline at any moment for any reason. And when that happens, you’re shit out of luck. The Stop Killing Games movement believes that if/when this happens, the publisher needs to have a plan in place to ensure that those games can continue to be played. This can take on many forms: modifying the game to not require an online connection, or releasing the server binaries so that players can host their own custom servers, or something of that nature. Worst comes worst, if none of this is possible, then the movement demands that it’s made clear in the game’s advertisement that you could lose game functionality when the servers shut down. Essentially, the laws surrounding game licenses are vague, and the movement wants a clarification on what buyers are entitled to when they buy a game.

The primary reason why many people have a misunderstanding of the movement is because a large YouTuber named PirateSoftware made 2 videos where he outright lied about what the movement was about and trashed it. He also made multiple statements on his streams where he purportedly “disproved” the movement, where he continued to lie about the movement and trashed it. His videos and statements were the most commonly viewed coverage on the movement, and this disinformation supposedly severely hampered the momentum of the movement, such that even now, many people still believe that the movement is about forcing publishers to keep their servers online indefinitely (it’s not).

PirateSoftware was a former developer at Blizzard and was making an online game at the time, so some people speculate that the reason he lied about the movement was because he had a vested interest in keeping the current vagueness of the laws. As more and more people attempted to call him out on his disinformation, he doubled down and refused to admit that he gave any sort of incorrect information, even when the information is provably incorrect.

Apparently, PirateSoftware has a history of this sort of behavior and has gotten himself into some previous scandals due to his seeming inability to admit that he was wrong at all. This has led otherwise minor, forgettable mistakes to balloon into giant controversies.

Taken together with this recent controversy with Stop Killing Games, his reputation has taken a significant nosedive and many people now believe that he’s a narcissist who is willing to take down the movement for the sole purpose that he wants to be seen as the smartest guy in the room.

No point in being doomer about it. We try whatever we need to in order to get the population to understand.

And for what it’s worth, it kind of makes sense. Science communication is generally quite poor. Scientists aren’t trained in PR or in communicating with the public. To some extent, it makes sense that the public doesn’t understand. In the longer term, it would certainly be better to raise scientific literacy. In the short term, we simply need quippy talking points that can be repeated to get the message to stick.

Are you confusing fahrenheit and Celsius? Body temp can’t cook food

Heavily context dependent, I’d say. In a vacuum, it’s not that unusual. The entire purpose of text is that you don’t have to respond immediately. If it happens constantly, then maybe it would have been worth figuring out why that keeps happening. Maybe he dislikes you, or maybe he’s just busy.

It seems you already understand that, though. So perhaps the more informative question is why you feel the way that you feel towards your ex. Frankly, it’s probably some level of infatuation (or as I call it, puppy love). It’s not intrinsically bad, but it does tend to drive people to have unrealistic expectations for their partners, which can drive conflict once those expectations become established

You can blindly download and install things from the internet on Windows, you can’t in Linux. If you try, it’ll be confusing at best, destructive at worst. If you want to install something, best to look for it in your GUI software manager (the “app store”)

If you’re up for the challenge (it’s extremely tedious to set up, partially thanks to its horrid instructions), you can try installing winapps. It’ll save you a lot of time with running Windows programs

I struggled with your exact same problem when I moved to Linux. For the record, the reason why there isn’t a Program Files x86 is because the way that Linux stores programs is different from the way that Windows stores programs. Windows sorts its system files by programs, so that the configuration, launcher, and software files are all together. Linux sorts by file type, so that the configuration files of all programs are together, the launchers of all programs are together, etc.

What I’ve come to learn is, don’t bother trying to find your application in the folder. The best way to install things is through Discover (or whatever GUI software manager you’re using). If the program you want isn’t there, it’s basically a crapshoot whether installing from the internet will work or not

The Sun god demands more sacrifices

No, unless you already know how to pilot the ship, playing in VR is probably going to get you severely motion sick

I’m unsure what you mean by switches, since all mechanical keyboards use switches.

Regardless, if you’re looking for a relatively cheap, good quality mechanical keyboard, I’d probably recommend you check out Keychron. They’ve got a lot of options and they’re all decent quality for a decent price, so you could probably find something you want in their catalog

The beam is clearly decorative. The smaller posts having variable width shows that this bridge was made beyond purely utilitarianism in mind. The bridge still looks to be a generic overpass, so I wonder if this bridge exists in real life. It would not surprise me if there were other decorative elements not shown in the drawing

Sure, but the overall intent holds true. Not just in professional settings, it’s important to have the skill to reframe a negative comment into a positive one.

This is probably what I would say:

It sounds like you’ve got everything you need for the meeting. Would it still make sense for me to attend?

If that’s the case, then I think I’d be more useful handling some other tasks in the meantime. Please keep me updated on the outcome of the meeting