Stevia is considered a “natural non-caloric sweetener.” Saccharin and sucralose are considered “non-nutritive sweeteners” (few or no calories). Aspartame is a “nutritive sweetener” (adds some calories but far less than sugar).
Aspartame comes with a warning to be used cautiously (or not at all) by people with a rare genetic disease (called phenylketonuria, or PKU) because they have trouble metabolizing it; that’s not true for the other sweeteners. And all four vary on their level of sweetness and aftertaste, which is likely why people often prefer one over another.
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https://www.health.harvard.edu/blog/sweeteners-time-to-rethink-your-choices-2019022215967

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