• thepianistfroggollum@lemmynsfw.com
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    1 year ago

    In a medical sense an overdose is just taking more than the recommended dose. That clear cut signal from your body is a symptom of an overdose.

    And yeah, the lethality of it is way over stated. Especially the “it can be super absorbed by the skin” stuff. I’ve spilt 250mg of nicotine on my hands and left it for a few minutes before washing it off, and all that happened was the spot was tingly for a minute or two.

    • barsoap@lemm.ee
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      1 year ago

      But then there wouldn’t be a difference between a plain junkie and someone who overdoses on heroin. The medically recommended dose of diamorphine in both cases was zero.

      What distinguishes those two cases is that one exceeded the effective dose. “Recommended dose” here doesn’t mean “what a doctor tells you” but “more than needed to achieve an intended effect”. For some getting past the boosting effect of nicotine into the depressing effect range might be an overdose. Yet others might enjoy some brief dizziness in an armchair.

      Toxicologically speaking nicotine has quite low overdose toxicity because any serious symptoms happen way after any desirable symptom. Toxicity, though, is what pedestrians generally think of when they hear “overdose” so that is what I focussed on.