cross-posted from: https://piefed.world/c/depression_now/p/933723/does-anybody-else-s-anti-depressants-wear-off-after-taking-a-nap-or-otherwise-sleeping

Duloxetine works great for me until I sleep, then I wake back up into the pit of despair and I feel like I’m supposed to wait until ~24 hours since I last took it in order to take it again. I can’t find any cases of other people reporting this and it’s not something my medical professionals have heard of. It makes it hard if I don’t have energy due to not getting enough sleep the night before so I take a nap, and then when I wake up I still don’t have energy due to lack of willpower. I’ve also found it harder to get out of bed in the morning shortly before taking the medicine.

  • dingus@lemmy.worldEnglish
    2·
    1 day ago

    How bizarre! Usually when I’m having a bad night, sleep helps me because the thoughts quiet down. I’ve been on a low dose of Seroquel. Bad thoughts can get to me at night but I seem to just fall asleep on the med which makes them go away and stay quiet into the next morning!

  • SavvyWolf@pawb.socialEnglish
    2·
    2 days ago

    I actually take my antidepressants right before I go to bed, and they seem to last the next day.

    I do get really upsetti if I stay up later than usual, and am generally lower in mood at night. But that could be a number of things.

    • dingus@lemmy.worldEnglish
      1·
      1 day ago

      Seems common enough to have a lower mood at night. Idk why really but I’ve always been the same.

  • emotional_soup_88@programming.devEnglish
    2·
    2 days ago

    If you need Duloxetine in order to sleep, then I don’t know… Otherwise, I do this: I take Sertraline in the morning when I wake up and it last the whole day. Then, when I need to sleep - and if I’m unable to sleep because kdw anxiety - I take Zoplicone, which knocks me out. It’s not an antidepressant nor is it ani anxiety medicine, it just induces sleep.