Psh. “Cardiovascular concerns.” Fucking read the side effects for the drugs you’ve already approved, FDA. You’ve allowed an autoimmune treatment drug that has a high chance of giving terminal fucking cancer, you dumb fucks. Fucking Viagra has “cardiovascular concerns.”
Biased, bought, dumb-asses.
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Nah, that’s not the issue (nor do I believe in magic bullets, but that’s a different matter). See, the issue is that MDMA can’t be patented. Anyone can make it so no one pharmacorp can have a 20 year monopoly
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You sound like you’d be interested in David Healy’s work. Check out Children of the Cure if you haven’t already. That, as well as a plethora of other shady things I learned in university, are responsible for reorienting me toward public policy rather than becoming a practicing psychologist.
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Usually first to market work generics enjoys a year of exclusivity. Usually other companies abandon our back burnera project they don’t make to market first. There’s still money to be made. Just not as much.
I think you don’t quite understand the comment.
Current pharmaceuticals are usually a (life)long prescription. It’s not like antibiotics, where you get a dose for a few days or weeks and you’re done. Antidepressants have to be taken for years. Every day. That means revenue every day. It’s a treatment, not a cure.
MDMA on the other hand is a (potential) cure. You take it a few times under supervision and that’s it.
Problem is, this takes away customers from the former group. And that means, far less revenue from “traditional” psychopharmacology products. MDMA cannibalizes other drugs.
Well, I guess it’s not only that. Psychedelic drugs can really fuck you up, if you aren’t prepared. People talk about set and setting a lot.
I suspect that these drugs sure help a lot of people, but can also fuck a lot of people up really badly. It’s like, people who don’t go along well with these substances, avoid them instinctively.
Now, if someone would prescribe them, I’m pretty sure that a lot of people who are simply not prepared for it mentally (instead blindly trust the medics), would take them and get hurt pretty badly because of that.
That’s why its better to take them under medical supervision(at least for the first time). Just giving them someone is probably the dumbest thing you could do.
It’s not just supervision IMO.
I prepared myself for years before I took psilocybin for the first time, because I knew that it’s going to bring up all of the subconscious shit that I carried around. So I “cleaned” myself enough emotionally beforehand, before taking the fungus.
Now, imagine your typical asshole walks into your medical treatment facility and demands psilocybin. Sure, you can give them psilocybin, but you cannot give them the sense of respect and understanding in front of these drugs.
Edit: by “your typical asshole” i mean, the typical asshole that you would encounter daily. Not you personally or sth.
That’s why you shouldn’t just give it out to the Normie’s. It should only be taken with medical supervision.
These drugs are typically used for individual and group therapy sessions and not given as prescriptions to take at home. They’re basically just there to augment therapy sessions.
I do think they should be legalized and allowed for recreational use as well but your concerns aren’t really justified if you look at what existing therapeutic applications are like and what companies in the psychedelic space are trying to do right now.
Yeah, I guess you have a point.
Don’t use the word cure.
It does not have that potential. This should be downvoted to oblivion.
There is no such thing as “curing” a mental disorder/disability. Although it could theoretically help speed up recovery from temporary bouts of depression or post-traumatic stress (which is often labelled “PTSD” when it’s not), it cannot cure a lifelong disorder like depressive/mood disorders or PTSD & CPTSD. “Curing” a mental disorder would mean making you a completely different person, it’s inseparable from the rest of your brain – especially something that leans more into the “neurodivergence” idea, like ADHD or ASD/Autism, which both have imperfect yet effective treatments (ASD less so than ADHD), but “curing” such a thing would be impossible.
The only solution that helps people with disabilities is to make treatment in the form of pharmaceuticals, counselling, and other methods widely available and accessible over the long term – not to look for a cure. Not to say that MDMA can’t be used for that though, it definitely can, it’d just be misleading to call it a cure.
I mean if it has an effect on the heart it should be mentioned…in a study about MDMA’s effect on the heart…I don’t really know how 2 trials about MDMA’s psychiatric effects has much to with cardiovascular health. I mean, if you stretch it you can maybe say something about the cardiovascular effects in relation to anxiety, but that’s about it.
Addendum: somehow forgot to add “in relation to anxiety”
Yeah. Every drug has side effects; I’m saying that it’s a weak excuse for not approving it, considering all of the other crap FDA’s approved, with all of the other crap’s side effects. So label it, put a warning on it.
Cigarettes will most likely kill you if you smoke enough of them, and FDA still allows their sale even though they have no medical application. Same with alcohol; despite the alcohol industry’s efforts to link health benefits with alcohol consumption, there are as many studies showing there’s no verifiable link between any benefit and any amount of alcohol consumption. It’s a poison that dehydrates you and shrinks your brain a little every time you drink it. But it’s legal.
FDA is the only dyke preventing outright charlatanism by the pharma and medical device industries, but fuck them on this topic. They’re there to ensure companies don’t outright lie to consumers about benefits and risks; preventing access to risky behavior is not their job.
preventing access to risky behavior is not their job.
I disagree. Lots of people will listen if you tell them about the dangers of a specific medication, but few will understand. Especially if they have no background in medicine or pharmaceutics.
As a species, we’re horrible at statistical risk-based decision-making. My opinion is that we - as a society - should better educate and prepare children in statistical evaluation, and then as long as the behavior directly impacts only the individual, let people do what they want. The alternative is a morass of laws dictating personal behavior, with often unintended and arguably worse outcomes for society (c.f. The War on Drugs).
But in any case, FDA’s job is to dictate the actions of companies, and prevent as well they can companies lying to and misleading consumers. Its mission is not to dictate individual behavior. And nor should it be.
FDA is there to stop cigarette companies from arguing or advertising to consumers that smoking is healthy, or that it makes you dick bigger, or whatever they think can make sales. FDA does not make rules preventing you from smoking.
What they’re doing here is flexing control over a substance that has no giant, well-heeled organization pressuring them to allow companies to sell it.
I will note that I’m not an MDMA advocate; I’ve consumed a variety of chemicals, some in numerous quantities, but I’ve never knowingly taken MDMA. So my argument doesn’t come from being butt-hurt about targeting my favorite drug; it’s about the hypocrisy in the FDA wording of their warning.
Oh, I’ll add: FDA doesn’t make laws, but they’re listened to by, and provide guidance for, lawmakers. And they do make decisions that decide whether a pharmaceutical or medical device company can bring a product to market, so they control legal supply. And this is only in the US, of course; the each country has their own version, and the EU has dozens from which corporations can pick and “give business to” to get approval to sell in that market.
There is this game where you get a million dollars with 99% probability and die a gruesome death with 1% probability if you press a certain button.
What would you do in that case?
IMO, statistics isn’t everything, and one cannot only rely on statistics to make meaningful decisions. Lots of people I know wouldn’t press that button.
Ah, but I disagree! The “gruesome” part is what changes it; it’s an important detail in Pascal’s Wager. If it were a sudden, painless death? I’d absolutely press it. If it meant death by being buried alive in a coffin? I wouldn’t press it if the odds were 1,000:1, or 10,000:1. The “badness” vs “goodness” factor of each certainly factors into the decision process. The benefit would have to be enormous to outweigh the consequence of a long, terrifying, and/or painful death. Far more than money, for me.
But it if were even 50:1 odds, and the penalty is a sudden and painless death, vs the world being contacted and accepted into Iain Bank’s The Culture? Heck yeah, gimme the button. I might take even worse odds.
And yet, I’m human, and humans are terrible at making decisions based on statistical odds; I’m maybe a little better than average for an American, but only because I have a formal process for making decisions like this. But I don’t apply it intuitively to every risk, so I’m as bad as anyone else, in general.
Imagine that (hypothetical scenario) MDMA heals 70% of people, doesn’t do anything for 10% of people, but throws 20% of people into mental disturbances.
Would you take it?
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Just use magic mushrooms.
Totally safe, effective against PTSD,
Endorsed twice as a “breakthrough drug” by the FDA.
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One perfectly safe dose of psilocybin instantly treats depression, anxiety and PTSD for more than 6 months at 80% efficacy, improving sociability, open-mindedness, resetting traumatic patterns, what are the numbers for MDMA, which is more physiologically dangerous and more difficult to apply in therapy?
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Okay, you can be personally excited about therapeutic MDMA possibilities without making up a "gold standard’.
The study I’ve linked to above is specifically for psilocybin treating PTSD with an 80% efficacy rate after one entirely safe dose for 6 to 12 months.
The link you’ve supplied, as far as I can tell, does not report conclusive results for MDMA treating PTSD.
MDMA is not a gold standard, it’s one non-standardized psychedelic therapeutic possibility that is physiologically more dangerous with fewer studies, more risks and more time commitment, therapeutic prerequisites and necessary conditions than psilocybin, without the resulting necessary controlled and conclusive clinical trials providing evidence of effective treatment.
I stand by my original point of seeing little reason to focus on more dangerous, less effective therapies when we already have a completely safe, simpler and so far more effective therapy according to conclusive controlled studies and patient testimony.
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I’m glad you read that article closely, although they specifically mentioned that the scientists chose terminally ill cancer patients because the symptoms are identical to the symptoms of post-traumatic stress disorder, and some of the patients in that study had comorbid PTSD.
There are studies going on right now with victims of domestic violence and veterans with PTSD.
I like all the drugs you’re suggesting, and I think people should be able to choose, although I maintain that the logical therapeutic focus should be on the one completely safe, easily administered and controlled drug proven to be effective in treating depression, anxiety, and especially the traumatic symptoms of post-traumatic stress disorder.
People should do whatever drugs they want, but that doesn’t make whatever drug they want the best choice for therapy right now.
We have a safe drug for that already. Psilocybin. It has passed every test so far, and it’s completely non-toxic.
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I miss good mdma
I know! I’m past the point in my life where I wanna rave, but I feel sorry for kids these days. Who knows what’s stuff actually is anymore what with bath salts and fentanyl. Sucks for the chillen. I had some really good times in barn raves out on the prarie
I don’t want anyone to take this as an endorsement of recreational drugs, but it sucks you gotta risk od and brain damage to do some molly.
Peer review is important.
