• HollowNaught@lemmy.world
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    3 hours ago

    I’m currently writing a small literature review on tgf-b and SMAD signalling in cancer for uni rn

    And I’m really confused why this one paper’s talking about how miR-520h induces the tgf-b/smad7 pathway but also binds to and suppresses smad7

    Like why on earth is it activating the tgf-b/smad7 pathway, a pathway that stops stuff like the epithelial mesenchynal transition, if it’s just going to bind to smad7 anyway???

    Worst thing is, I can’t find any other papers on why this actually happens

    I swear I’m just dumb at times ;-;